Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.40 |
| ▸ | TOP2A | P11388 | 4/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878164 | 1.00 | GSK3B (0.40) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL6877382 | 0.87 | GSK3B (0.53) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL5236368 | 0.82 | GSK3B (0.50) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL501142 | 0.82 | GSK3B (0.50) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL7044371 | 0.81 | MEN1 (0.41) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL8007897 | 0.81 | GSK3B (0.45) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL8744082 | 0.81 | GSK3B (0.45) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL7997875 | 0.81 | GSK3B (0.45) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL7510517 | 0.79 | TOP2A (0.38) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL7510524 | 0.79 | TOP2A (0.38) | GSK3BTOP2ATOP2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825353-B2 | AN AMINE SUBSTITUENT AT THE 7-POSITION OF THE QUINOLONE-CARBOXYLIC ACID DERIVATIVE IS PRODUCED; BACTERICIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030060631-A1 | Process for producing quinolonecarboxlic acids and intermediates thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030060631-A1 | Process for producing quinolonecarboxlic acids and intermediates thereof | NQO2, QPCT, QARS1 | GSK3B 1080/4885TOP2A 747/4885TOP2B 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.