Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.45 |
| ▸ | TOP2A | P11388 | 4/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744082 | 1.00 | GSK3B (0.45) | GSK3BTOP2ATOP2BSTAT3MEN1 | |
| SCHEMBL8007897 | 1.00 | GSK3B (0.45) | GSK3BTOP2ATOP2BSTAT3MEN1 | |
| SCHEMBL8131981 | 0.90 | STAT3 (0.56) | GSK3BTOP2ATOP2BSTAT3MEN1 | |
| SCHEMBL9096957 | 0.90 | STAT3 (0.56) | GSK3BTOP2ATOP2BSTAT3MEN1 | |
| SCHEMBL8131449 | 0.90 | STAT3 (0.56) | GSK3BTOP2ATOP2BSTAT3MEN1 | |
| SCHEMBL4675138 | 0.86 | STAT3 (0.49) | GSK3BTOP2ATOP2BSTAT3MEN1 | |
| SCHEMBL4730859 | 0.86 | STAT3 (0.49) | GSK3BTOP2ATOP2BSTAT3MEN1 | |
| SCHEMBL5619172 | 0.85 | GSK3B (0.53) | GSK3BTOP2ATOP2BSTAT3MEN1 | |
| SCHEMBL8139161 | 0.85 | GSK3B (0.53) | GSK3BTOP2ATOP2BSTAT3MEN1 | |
| SCHEMBL4673103 | 0.85 | GSK3B (0.53) | GSK3BTOP2ATOP2BSTAT3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593766-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5696132-A | MICROBIOCIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0593766-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |