Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 0.64 |
| ▸ | FNTB | P49356 | 14/20 | 0.64 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.64 |
| ▸ | NRAS | P01111 | 1/20 | 0.51 |
| ▸ | HRAS | P01112 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048954 | 0.85 | FNTA (0.63) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL7047035 | 0.78 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL7744284 | 0.76 | FNTA (0.58) | FNTAFNTBPGGT1BKCNH2 | |
| Hydrochloric Acid SCHEMBL8479762 | 0.75 | FNTA (0.57) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL5891541 | 0.72 | FNTA (0.63) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL8184482 | 0.72 | FNTA (0.62) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL7054747 | 0.70 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL7847959 | 0.70 | FNTA (0.60) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7976856 | 0.70 | FNTA (0.57) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL2786255 | 0.69 | CYP11B1 (0.71) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216441-A1 | Farnesyltransferase inhibitors | WEINSTOCK, STEVEN F. | 2003-11-20 | — | — | US | claimed |
| US-20030216441-A1 | Farnesyltransferase inhibitors | WEINSTOCK, STEVEN F. | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216441-A1 | Farnesyltransferase inhibitors | FNTA, FNTB, LCAT | FNTA 1/4885FNTB 2/4885PGGT1B 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.