SCHEMBL7046932

SCHEMBL7046932

CCOC(=O)CCCCCCCCC(N)=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.65
DGKA P23743 1/20 0.54
ALOX15 P16050 3/20 0.53
ALDH1A1 P00352 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
TSHR P16473 2/20 0.53
CYP3A4 P08684 2/20 0.53
HSD17B10 Q99714 1/20 0.53
GAA P10253 2/20 0.52
PAM P19021 2/20 0.48
MGAM O43451 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
USP2 O75604 1/20 0.47
KMT2A Q03164 2/20 0.47
NR1I2 O75469 1/20 0.47
PGR P06401 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
PTGS2 P35354 1/20 0.47
PDE4D Q08499 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31084214 1.00 CYP1A2 (0.65) CYP1A2DGKAALOX15ALDH1A1TDP1
SCHEMBL3043054 1.00 CYP1A2 (0.65) CYP1A2DGKAALOX15ALDH1A1TDP1
SCHEMBL31084215 1.00 CYP1A2 (0.65) CYP1A2DGKAALOX15ALDH1A1TDP1
SCHEMBL11305128 0.98 CYP1A2 (0.68) CYP1A2DGKAALOX15ALDH1A1TDP1
Hydrochloric Acid SCHEMBL2962204 0.95 CYP1A2 (0.65) CYP1A2DGKAALOX15ALDH1A1TDP1
Palmitamide SCHEMBL8397167 0.94 DGKA (0.64) CYP1A2DGKAALDH1A1TSHRCYP3A4
Octadecanoic Acid Amide SCHEMBL5457014 0.94 DGKA (0.64) CYP1A2DGKAALDH1A1TSHRCYP3A4
Palmitamide SCHEMBL8399904 0.94 DGKA (0.64) CYP1A2DGKAALDH1A1TSHRCYP3A4
SCHEMBL11076396 0.93 CYP1A2 (0.68) CYP1A2DGKAALOX15ALDH1A1TDP1
SCHEMBL6055406 0.91 CYP1A2 (0.70) CYP1A2DGKAALOX15ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003006426-A1 AROMATIC GUANYLHYDRAZONES AS EFFECTIVE COMPOUNDS AGAINST NEURODISEASES AXXIMA PHARMACEUTICALS AG (DE) 2003-01-23 WO disclosed