SCHEMBL7047401

SCHEMBL7047401

CCCCCCCCCCNCCC[Si](OC)(OC)OC

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
TSHR P16473 1/20 0.54
LMNA P02545 1/20 0.53
EPHX1 P07099 8/20 0.44
S1PR2 O95136 5/20 0.41
S1PR4 O95977 5/20 0.41
S1PR1 P21453 5/20 0.41
S1PR3 Q99500 5/20 0.41
S1PR5 Q9H228 1/20 0.41
ADH1B P00325 1/20 0.40
ADH1C P00326 1/20 0.40
ADH1A P07327 1/20 0.40
ADH4 P08319 1/20 0.40
ADH7 P40394 1/20 0.40
SIGMAR1 Q99720 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13146321 1.00 ALDH1A1 (0.54) ALDH1A1TSHRLMNAEPHX1S1PR2
SCHEMBL1123064 1.00 ALDH1A1 (0.54) ALDH1A1TSHRLMNAEPHX1S1PR2
SCHEMBL7043816 1.00 ALDH1A1 (0.54) ALDH1A1TSHRLMNAEPHX1S1PR2
SCHEMBL2713878 1.00 ALDH1A1 (0.54) ALDH1A1TSHRLMNAEPHX1S1PR2
SCHEMBL7044621 1.00 ALDH1A1 (0.54) ALDH1A1TSHRLMNAEPHX1S1PR2
SCHEMBL11675402 1.00 ALDH1A1 (0.54) ALDH1A1TSHRLMNAEPHX1S1PR2
SCHEMBL271359 1.00 ALDH1A1 (0.54) ALDH1A1TSHRLMNAEPHX1S1PR2
SCHEMBL3443515 1.00 ALDH1A1 (0.54) ALDH1A1TSHRLMNAEPHX1S1PR2
Hydrochloric Acid SCHEMBL1123187 0.98 ALDH1A1 (0.52) ALDH1A1TSHRLMNAEPHX1S1PR2
SCHEMBL8080842 0.98 ALDH1A1 (0.52) ALDH1A1TSHRLMNAEPHX1S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0983279-B1 N-SUBSTITUTED-.OMEGA.-(ALKOXYSILYL)ALKYLAMINES AND PROCESS FOR PRODUCTION THEREOF BAYER INC (CA) 2003-04-09 EP disclosed
US-6310230-B1 AMINATING A (HALOHYDROCARBYL)(ALKOXY)SILANE OR HYDROCARBYLATING AN (AMINOHYDROCARBYL)(ALKOXY)SILANE BAYER INC. (CA) 2001-10-30 US disclosed