Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 8/20 | 0.34 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.34 |
| ▸ | ESRRG | P62508 | 3/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ESRRB | O95718 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904290 | 0.83 | PLK1 (0.34) | RARBPLK1ESRRGNR1H4KCNH2 | |
| SCHEMBL7042952 | 0.74 | NPC1 (0.31) | NPC1RAB9ATP53POLBNFKB1 | |
| SCHEMBL6904432 | 0.74 | TRPV1 (0.37) | NPC1RAB9ARARBPLK1ESRRG | |
| SCHEMBL6905034 | 0.69 | ESRRG (0.30) | ESRRG | |
| SCHEMBL547838 | 0.67 | KCNH2 (0.60) | NPC1RAB9ATP53SMN1; SMN2PLK1 | |
| SCHEMBL6550678 | 0.64 | PLK1 (0.40) | RARBPLK1ESRRGNR1H4KCNH2 | |
| SCHEMBL15685935 | 0.63 | CNR2 (0.53) | CNR2NPC1RAB9ARARBPLK1 | |
| SCHEMBL9711161 | 0.63 | ESR1 (0.63) | TP53ESRRGKCNH2ESRRB | |
| SCHEMBL8776979 | 0.63 | KCNH2 (0.63) | TP53KCNH2 | |
| SCHEMBL28534367 | 0.61 | KCNH2 (0.61) | TP53KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296991-B1 | SILOXY SUBSTITUTED COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2013-05-15 | — | — | EP | disclosed |
| EP-1296991-A1 | SILOXY SUBSTITUTED COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION | ExxonMobil Chemical Patents Inc. (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-1297027-A1 | SILOXY SUBSTITUTED COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002000738-A1 | SILOXY SUBSTITUTED COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2002-01-03 | — | — | WO | disclosed |
| WO-2002000666-A1 | SILOXY SUBSTITUTED COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2002-01-03 | — | — | WO | disclosed |