Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047580 | 0.83 | CNR1 (0.36) | PLK1RARBESRRGNR1H4KCNH2 | |
| SCHEMBL6905034 | 0.81 | ESRRG (0.30) | ESRRG | |
| SCHEMBL6904432 | 0.73 | TRPV1 (0.37) | PLK1RARBESRRGTRPV1THRA | |
| SCHEMBL547838 | 0.65 | KCNH2 (0.60) | PLK1ESRRGKDM4EKCNH2 | |
| SCHEMBL7599381 | 0.64 | NPC1 (0.33) | — | |
| SCHEMBL6550678 | 0.63 | PLK1 (0.40) | PLK1RARBESRRGTRPV1THRA | |
| SCHEMBL9711161 | 0.62 | ESR1 (0.63) | ESRRGKDM4EKCNH2 | |
| SCHEMBL15685933 | 0.61 | CNR2 (0.54) | PLK1RARBESRRGTRPV1THRA | |
| SCHEMBL8776979 | 0.61 | KCNH2 (0.63) | TRPV1KDM4ETNNC1S1PR1SGPL1 | |
| SCHEMBL5166701 | 0.61 | NPC1 (0.56) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806220-B2 | COORDINATION CATALYST FOR POLYOLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-10-19 | — | — | US | claimed |