SCHEMBL7047718

SCHEMBL7047718

CCC1=Cc2c(-c3ccccc3)cccc2C1[Zr](C)(C)(=[SiH2])C1C(CC)=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL272677 0.99
Fluoride SCHEMBL7637307 0.99
SCHEMBL4002684 0.91 PDCD1 (0.33) PDCD1CD274
Hydrochloric Acid SCHEMBL6065714 0.88
Hydrochloric Acid SCHEMBL6065881 0.88 EDNRB (0.33)
Hydrochloric Acid SCHEMBL2508972 0.88 ADRB2 (0.30)
SCHEMBL4008013 0.88 PDCD1 (0.32) PDCD1CD274
Hydrochloric Acid SCHEMBL8605095 0.87
SCHEMBL3891684 0.86 PDCD1 (0.30) PDCD1CD274
Hydrochloric Acid SCHEMBL2513705 0.86 BCHE (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859800-B1 SUPPORTED CATALYST SYSTEM, PROCESS FOR ITS PRODUCTION AND ITS USE IN POLYMERISING OLEFINES BASELL POLYOLEFINE GMBH (DE) 2003-07-23 EP claimed
EP-1058694-B1 Catalyst system, method for its production and its use for the polymerisation of olefins BASELL POLYOLEFINE GMBH (DE) 2003-04-09 EP claimed
US-6583227-B2 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2003-06-24 US disclosed
US-20020160914-A1 Highly active supported catalyst compositions EXXONMOBIL CHEMICAL PATENTS INC. 2002-10-31 US disclosed
US-20010044506-A1 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-22 US disclosed
US-6177376-B1 REACTING METALLOCENE WITH ORGANOLITHIUM COMPOUND AND GRIGNARD COMPOUND, ACTIVATION, CONTACTING WITH SUPPORT TARGOR GMBH (DE) 2001-01-23 US disclosed