Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30542040 | 0.82 | PIK3CD (0.39) | PIK3CDASPHRPS6KA5ADRB2XPO1 | |
| SCHEMBL6739131 | 0.80 | PIK3CD (0.45) | PIK3CDASPHRPS6KA5ALDH1A1CYP1A2 | |
| SCHEMBL677228 | 0.80 | PIK3CD (0.38) | PIK3CDASPHRPS6KA5CYP1A2LRRK2 | |
| SCHEMBL6740290 | 0.80 | PIK3CD (0.38) | PIK3CDASPHRPS6KA5XPO1CYP1A2 | |
| SCHEMBL30833528 | 0.78 | CYP3A4 (0.30) | — | |
| SCHEMBL9574504 | 0.78 | CYP3A4 (0.30) | — | |
| SCHEMBL29137108 | 0.77 | PIK3CD (0.36) | PIK3CDRPS6KA5ALDH1A1CYP1A2LRRK2 | |
| SCHEMBL5942453 | 0.76 | PDXK (0.42) | PIK3CDASPHALDH1A1XPO1 | |
| SCHEMBL31319309 | 0.73 | PIK3CD (0.46) | PIK3CDASPHRPS6KA5ALDH1A1ADRB2 | |
| SCHEMBL31214152 | 0.73 | PIK3CD (0.39) | PIK3CDASPHRPS6KA5ADRB2XPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050362-A1 | PREPARATION OF 2,5-DICHLORO-(3-TRIFLUOROMETHYL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 1998-11-12 | — | — | WO | claimed |
| EP-0204535-B1 | N-FLUOROPYRIDINIUM SALT AND PROCESS FOR PREPARING SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-08-19 | — | — | EP | claimed |
| EP-1296952-A1 | BENZOYLPYRIDINE DERIVATIVE OR ITS SALT, FUNGICIDE CONTAINING IT AS AN ACTIVE INGREDIENT, ITS PRODUCTION PROCESS AND INTERMEDIATE FOR PRODUCING IT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002002527-A1 | BENZOYLPYRIDINE DERIVATIVE OR ITS SALT, FUNGICIDE CONTAINING IT AS AN ACTIVE INGREDIENT, ITS PRODUCTION PROCESS AND INTERMEDIATE FOR PRODUCING IT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2002-01-10 | — | — | WO | disclosed |
| WO-1998050362-A1 | PREPARATION OF 2,5-DICHLORO-(3-TRIFLUOROMETHYL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 1998-11-12 | — | — | WO | disclosed |
| US-RE35177-E | N-fluoropyridinium salt and process for preparing same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0494770-B1 | Method for preparing N-fluoropyridinium salts | ONODA CEMENT CO LTD (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5336772-A | Reacting pyridine compound, fluorine and Bronsted acid in specified ratios | ONODA CEMENT CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0204535-B1 | N-FLUOROPYRIDINIUM SALT AND PROCESS FOR PREPARING SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-08-19 | — | — | EP | disclosed |
| EP-0494770-A1 | Method for preparing N-fluoropyridinium salts | ONODA CEMENT COMPANY, LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-4996320-A | Thyroid inhibitors | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-02-26 | — | — | US | disclosed |
| EP-0204535-A1 | N-fluoropyridinium salt and process for preparing same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-12-10 | — | — | EP | disclosed |