SCHEMBL7047987 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	PTGS2	P35354	10/20	0.47

▸	PTGS1	P23219	3/20	0.37

▸	F10	P00742	2/20	0.35

▸	F2	P00734	1/20	0.35

▸	BRD4	O60885	2/20	0.34

▸	CA2	P00918	3/20	0.33

▸	CA1	P00915	2/20	0.33

▸	CA7	P43166	2/20	0.33

▸	CA4	P22748	2/20	0.33

▸	IDO1	P14902	1/20	0.32

▸	BRD2	P25440	1/20	0.32

▸	BRD3	Q15059	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6721956	0.97	PTGS2 (0.50)	PTGS2PTGS1F10F2BRD4
SCHEMBL6730307	0.94	PTGS2 (0.53)	PTGS2PTGS1F10F2BRD4
SCHEMBL6729327	0.88	PTGS2 (0.55)	PTGS2PTGS1F10F2BRD4
SCHEMBL6725773	0.88	PTGS2 (0.47)	PTGS2PTGS1F10F2BRD4
SCHEMBL6721852	0.88	PTGS2 (0.47)	PTGS2PTGS1F10F2BRD4
SCHEMBL6722859	0.88	PTGS2 (0.44)	PTGS2PTGS1BRD4
SCHEMBL6718506	0.87	PTGS2 (0.51)	PTGS2PTGS1BRD4CA2CA1
SCHEMBL6725950	0.86	PTGS2 (0.50)	PTGS2PTGS1F10F2BRD4
SCHEMBL6722911	0.86	PTGS2 (0.53)	PTGS2PTGS1F10F2BRD4
SCHEMBL6719265	0.85	PTGS2 (0.49)	PTGS2PTGS1F10F2BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1296971-A2	2-FLUOROBENZENESULFONYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION	Pharmacia Corporation (US)	2003-04-02	—	—	EP	disclosed
WO-2001081332-A2	2-FLUOROBENZENESULFONYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION	PHARMACIA CORPORATION (US)	2001-11-01	—	—	WO	disclosed