Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | YWHAH | Q04917 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111374 | 0.91 | HTT (0.52) | BCHELMNAALDH1A1DNM1MEN1 | |
| SCHEMBL7055987 | 0.90 | HTT (0.55) | BCHELMNAALDH1A1DNM1MEN1 | |
| SCHEMBL27593038 | 0.89 | DNM1 (0.55) | BCHEALDH1A1DNM1MEN1KMT2A | |
| SCHEMBL7054663 | 0.89 | DNM1 (0.55) | BCHEALDH1A1DNM1MEN1KMT2A | |
| SCHEMBL7048773 | 0.89 | DNM1 (0.54) | BCHELMNAALDH1A1DNM1MEN1 | |
| SCHEMBL27576822 | 0.88 | DNM1 (0.49) | BCHEALDH1A1DNM1YWHAHMEN1 | |
| SCHEMBL7055848 | 0.88 | DNM1 (0.49) | BCHEALDH1A1DNM1YWHAHMEN1 | |
| SCHEMBL7112618 | 0.88 | DNM1 (0.49) | BCHEALDH1A1DNM1YWHAHMEN1 | |
| SCHEMBL7115591 | 0.87 | DNM1 (0.48) | BCHEALDH1A1DNM1MEN1KMT2A | |
| SCHEMBL7053205 | 0.84 | DNM1 (0.49) | BCHEDNM1MEN1KMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |