Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.71 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | ARG2 | P78540 | 4/20 | 0.46 |
| ▸ | ARG1 | P05089 | 3/20 | 0.46 |
| ▸ | NOS1 | P29475 | 4/20 | 0.45 |
| ▸ | NOS2 | P35228 | 4/20 | 0.45 |
| ▸ | NOS3 | P29474 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL7048440 | 1.00 | GSR (0.71) | GSRGRIK1GRIK2SLC1A2SLC1A1 | |
| Lysine SCHEMBL7040784 | 0.87 | GSR (0.74) | GSRGRIK1GRIK2SLC1A2SLC1A1 | |
| Lysine SCHEMBL7037399 | 0.87 | GSR (0.74) | GSRGRIK1GRIK2SLC1A2SLC1A1 | |
| Lysine SCHEMBL1962211 | 0.86 | GSR (0.67) | GSRGRIK1GRIK2SLC1A2SLC1A1 | |
| Lysine SCHEMBL1962209 | 0.86 | GSR (0.67) | GSRGRIK1GRIK2SLC1A2SLC1A1 | |
| Lysine SCHEMBL1671166 | 0.85 | GSR (0.83) | GSRGRIK1GRIK2SLC1A2SLC1A1 | |
| Lysine SCHEMBL27844690 | 0.85 | GSR (0.83) | GSRGRIK1GRIK2SLC1A2SLC1A1 | |
| Lysine SCHEMBL4667049 | 0.85 | GSR (0.83) | GSRGRIK1GRIK2SLC1A2SLC1A1 | |
| Lysine SCHEMBL31541159 | 0.85 | GSR (0.91) | GSRARG2ARG1NOS1NOS2 | |
| Lysine SCHEMBL18396696 | 0.85 | GSR (0.91) | GSRARG2ARG1NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727212-B2 | CONTACTING HARD SURFACE FOR A TIME SUFFICIENT TO SOFTEN SOIL WITH COMPOSITION COMPRISING HIGH PH SOIL SOFTENING ADDITIVE | THE PROCTER & GAMBLE COMPANY | 2004-04-27 | — | — | US | disclosed |
| US-20020039988-A1 | METHOD FOR SOFTENING SOIL ON HARD SURFACES | THE PROCTER & GAMBLE COMPANY | 2002-04-04 | — | — | US | disclosed |
| EP-1051470-A1 | METHOD FOR SOFTENING SOIL ON HARD SURFACES | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999024539-A1 | METHOD FOR SOFTENING SOIL ON HARD SURFACES | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-20 | — | — | WO | disclosed |