SCHEMBL7048566

SCHEMBL7048566

Cc1cc(C2C=CC3=C2C=CC=CC3)c2ccccc2c1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.37
CYP2A6 P11509 1/20 0.37
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7051304 0.85 HTR6 (0.36) CYP1A2CYP2A6
SCHEMBL6332120 0.71 CYP1A2 (0.44) CYP1A2CYP2A6
SCHEMBL7054455 0.68 CYP1A2 (0.34) CYP1A2CYP2A6
SCHEMBL7053084 0.68 CYP1A2 (0.34) CYP1A2CYP2A6NPC1RAB9A
SCHEMBL7048708 0.67 CYP1A2 (0.33) CYP1A2CYP2A6
SCHEMBL7051332 0.67 CYP1A2 (0.33) CYP1A2CYP2A6
SCHEMBL7053639 0.66 CYP1A2 (0.32) CYP1A2CYP2A6
SCHEMBL7048568 0.66 KDM1A (0.39) CYP2A6
SCHEMBL25795852 0.65 CYP2A6 (0.48) CYP1A2CYP2A6NPC1RAB9A
SCHEMBL7056298 0.65 CYP1A2 (0.31) CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985674-B1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS MITSUBISHI CHEM CORP (JP) 2003-04-23 EP disclosed
US-6255515-B1 COORDINATION POLYMERIZATION CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-03 US disclosed
EP-0985674-A1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS MITSUBISHI CHEMICAL CORPORATION (JP) 2000-03-15 EP disclosed