Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ERG | P11308 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | PPIB | P23284 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045869 | 0.91 | NAMPT (0.40) | NAMPTEGLN1TP53GPR119JAK2 | |
| SCHEMBL7049735 | 0.86 | F2 (0.40) | NAMPTTP53S1PR1PPIB | |
| SCHEMBL6476534 | 0.84 | JAK2 (0.36) | GPR119JAK2JAK1 | |
| SCHEMBL7989105 | 0.83 | NAMPT (0.39) | NAMPTEGLN1GPR119CYP3A4LMNA | |
| SCHEMBL7973611 | 0.80 | NAMPT (0.37) | NAMPTEGLN1TP53GPR119JAK2 | |
| SCHEMBL7045772 | 0.80 | JAK2 (0.40) | JAK2JAK1 | |
| SCHEMBL7045257 | 0.76 | DPP4 (0.37) | JAK2JAK1 | |
| SCHEMBL5901089 | 0.76 | EPHX1 (0.33) | — | |
| SCHEMBL6477215 | 0.76 | JAK2 (0.37) | NAMPTGPR119JAK2JAK1 | |
| SCHEMBL7049353 | 0.74 | F2 (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773955-B1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | BASF AG (DE) | 2003-04-16 | — | — | EP | disclosed |
| WO-1995035309-A1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-28 | — | — | WO | disclosed |