⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704435 | 0.73 | — | — | |
| SCHEMBL564706 | 0.70 | — | — | |
| SCHEMBL1325781 | 0.67 | — | — | |
| SCHEMBL8431282 | 0.67 | — | — | |
| SCHEMBL706613 | 0.67 | — | — | |
| SCHEMBL706180 | 0.67 | — | — | |
| SCHEMBL1325612 | 0.65 | — | — | |
| SCHEMBL8092379 | 0.62 | TSHR (0.33) | — | |
| SCHEMBL15526620 | 0.53 | ALDH1A1 (0.30) | — | |
| SCHEMBL28014 | 0.53 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2647641-A1 | New methods for the preparation of taxanes using chiral auxiliaries | Accord Healthcare Inc. (CA) | 2013-10-09 | — | — | EP | disclosed |
| EP-1948669-B1 | NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES | ACCORD HEALTHCARE INC (CA) | 2013-07-10 | — | — | EP | disclosed |
| US-8207358-B2 | Methods for the preparation of taxanes using chiral auxiliaries | ACCORD HEALTHCARE LTD. (CA) | 2012-06-26 | — | — | US | disclosed |
| US-8207358-B2 | Methods for the preparation of taxanes using chiral auxiliaries | ACCORD HEALTHCARE LTD. (CA) | 2012-06-26 | — | — | US | disclosed |
| US-8124239-B2 | Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same | FUJITSU LIMITED (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20110065912-A1 | NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES | ACCORD HEALTHCARE LTD. (CA) | 2011-03-17 | — | — | US | disclosed |
| US-20110065912-A1 | NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES | ACCORD HEALTHCARE LTD. (CA) | 2011-03-17 | — | — | US | disclosed |
| US-20110054191-A1 | NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES | ACCORD HEALTHCARE LTD. (CA) | 2011-03-03 | — | — | US | disclosed |
| US-20110054191-A1 | NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES | ACCORD HEALTHCARE LTD. (CA) | 2011-03-03 | — | — | US | disclosed |
| US-20100155121-A1 | SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME | FUJITSU LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| US-7659357-B2 | Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed | FUJITSU LIMITED (JP) | 2010-02-09 | — | — | US | disclosed |
| US-20090137796-A1 | METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES | BIOXEL PHARMA INC. (CA) | 2009-05-28 | — | — | US | disclosed |
| US-20090137796-A1 | METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES | BIOXEL PHARMA INC. (CA) | 2009-05-28 | — | — | US | disclosed |
| EP-1948669-A1 | NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES | Bioxel Pharma Inc. (CA) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007051306-A1 | NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES | BIOXEL PHARMA INC. (CA) | 2007-05-10 | — | — | WO | disclosed |
| US-20070026689-A1 | Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same | FUJITSU LIMITED (JP) | 2007-02-01 | — | — | US | disclosed |
| US-6800751-B2 | ALKYLATION OF 2'-HYDROXY GROUP OF RIBONUCLEOSIDE PROTECTED WITH INVENTIVE SILYLATING AGENTS IN PRESENCE OF EXCESS OF MILD HINDERED BASE MAY BE CARRIED OUT WITHOUT PROTECTING EXOCYCLIC AMINE AND OXO FUNCTIONALITIES OF NUCLEOBASES | ISIS PHARMACEUTICALS, INC. | 2004-10-05 | — | — | US | disclosed |
| US-20030225262-A1 | Reagent and process for protecting active groups | IONIS PHARMACEUTICALS, INC. | 2003-12-04 | — | — | US | disclosed |
| WO-2003087053-A2 | REAGENT AND PROCESS FOR PROTECTING NUCLEOSIDE ACTIVE GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 2003-10-23 | — | — | WO | disclosed |