Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | TEC | P42680 | 1/20 | 0.51 |
| ▸ | TXK | P42681 | 1/20 | 0.51 |
| ▸ | BMX | P51813 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433911 | 0.86 | BTK (0.58) | BTKEGFRTECTXKBMX | |
| SCHEMBL7136337 | 0.85 | BTK (0.60) | BTKEGFR | |
| SCHEMBL7048634 | 0.84 | BTK (0.56) | BTKEGFRTECTXKBMX | |
| SCHEMBL6430448 | 0.82 | BTK (0.64) | BTKEGFRTECTXKBMX | |
| SCHEMBL7133355 | 0.80 | BTK (0.62) | BTKEGFRTECTXKBMX | |
| SCHEMBL7140714 | 0.79 | BTK (0.60) | BTKEGFR | |
| SCHEMBL7144296 | 0.78 | BTK (0.73) | BTKEGFRTECTXKBMX | |
| SCHEMBL5801655 | 0.75 | BTK (0.71) | BTKEGFRTECTXKBMX | |
| SCHEMBL7046503 | 0.74 | BTK (0.69) | BTKEGFRTECTXKBMX | |
| SCHEMBL7141273 | 0.74 | BTK (0.67) | BTKEGFRTECTXKBMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004100868-A2 | METHOD OF TREATING TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2004-11-25 | — | — | WO | disclosed |
| US-6660744-B1 | Kinase inhibitors | ABBOTT GMBH & CO. KG (DE) | 2003-12-09 | — | — | US | disclosed |