Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.60 |
| ▸ | EGFR | P00533 | 4/20 | 0.60 |
| ▸ | LCK | P06239 | 3/20 | 0.60 |
| ▸ | ITK | Q08881 | 2/20 | 0.60 |
| ▸ | JAK3 | P52333 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140714 | 0.91 | BTK (0.60) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL6432266 | 0.86 | BTK (0.62) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL7048636 | 0.85 | BTK (0.56) | BTKEGFR | |
| SCHEMBL7133355 | 0.84 | BTK (0.62) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL7136335 | 0.84 | BTK (0.60) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL6432745 | 0.83 | BTK (0.64) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL7047810 | 0.83 | BTK (0.60) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL6438149 | 0.82 | BTK (0.70) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL7141273 | 0.82 | BTK (0.67) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL7140710 | 0.81 | BTK (0.61) | BTKEGFRLCKITKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660744-B1 | Kinase inhibitors | ABBOTT GMBH & CO. KG (DE) | 2003-12-09 | — | — | US | disclosed |