Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.40 |
| ▸ | BRAF | P15056 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781138 | 0.94 | KDR (0.42) | KDRBRAFKCNH2HTR2ASLC6A4 | |
| SCHEMBL7776101 | 0.94 | KDR (0.42) | KDRBRAFKCNH2HTR2ASLC6A4 | |
| SCHEMBL7781098 | 0.92 | KDR (0.40) | KDRBRAFMAPK14TNNI3KFLT1 | |
| SCHEMBL7776073 | 0.89 | KDR (0.48) | KDRBRAFMAPK14TNNI3KFLT1 | |
| SCHEMBL7780255 | 0.89 | KDR (0.46) | KDRBRAFMAPK14TNNI3KFLT1 | |
| SCHEMBL7783042 | 0.83 | KDR (0.45) | KDRBRAFMAPK14TNNI3KSMN1; SMN2 | |
| SCHEMBL6938479 | 0.82 | KDR (0.48) | KDRBRAFFLT1FLT4KCNH2 | |
| SCHEMBL7056169 | 0.81 | KDR (0.40) | KDRBRAFMAPK14TNNI3KFLT1 | |
| SCHEMBL7885594 | 0.78 | KDR (0.46) | KDRBRAFFLT1FLT4KCNH2 | |
| SCHEMBL7782975 | 0.78 | RAF1 (0.39) | KDRBRAFFLT1FLT4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972447-B1 | Parasitic and saprophagous mite control on beneficial insects | BASF AG (DE) | 2003-05-02 | — | — | EP | claimed |
| US-6342499-B1 | INSECTICIDES AND MITICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-29 | — | — | US | claimed |
| EP-0972770-B1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | BASF AG (DE) | 2001-09-19 | — | — | EP | claimed |
| US-6281219-B1 | 4,6-BIS-ARYL-PYRIMIDINES WHEREIN THE AROMATIC GROUPS ARE ATTACHED VIA TWO LINKING GROUPS WHICH ARE DIFFERENT FROM ONE ANOTHER. | AMERICAN CYANAMID CO. | 2001-08-28 | — | — | US | claimed |
| EP-0972770-A1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | American Cyanamid Company (US) | 2000-01-19 | — | — | EP | claimed |
| EP-0972447-B1 | Parasitic and saprophagous mite control on beneficial insects | BASF AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| US-6342499-B1 | INSECTICIDES AND MITICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-29 | — | — | US | disclosed |
| US-6281219-B1 | 4,6-BIS-ARYL-PYRIMIDINES WHEREIN THE AROMATIC GROUPS ARE ATTACHED VIA TWO LINKING GROUPS WHICH ARE DIFFERENT FROM ONE ANOTHER. | AMERICAN CYANAMID CO. | 2001-08-28 | — | — | US | disclosed |
| EP-0972447-A2 | Parasitic and saprophagous mite control on beneficial insects | American Cyanamid Company (US) | 2000-01-19 | — | — | EP | disclosed |