Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9355931 | 0.97 | TSHR (0.60) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL5519538 | 0.92 | TSHR (0.68) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL5518161 | 0.92 | TSHR (0.68) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL6816127 | 0.92 | TSHR (0.68) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL7980391 | 0.92 | TSHR (0.68) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL5514816 | 0.92 | TSHR (0.68) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL5519415 | 0.92 | TSHR (0.68) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL5515745 | 0.92 | TSHR (0.68) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL11516419 | 0.92 | ALDH1A1 (0.56) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL19329177 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778712-B1 | 2-PROPYNYL ADENOSINE ANALOGS WITH MODIFIED 5'-RIBOSE GROUPS HAVING A2A AGONIST ACTIVITY | Univ Virginia Patent Found (US) | 2013-01-30 | — | — | EP | disclosed |
| WO-2003015706-A2 | BORINIC ACID PROTEASE INHIBITORS | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2003-02-27 | — | — | WO | disclosed |