Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 7/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051773 | 0.93 | BACE1 (0.49) | DNM1MEN1KMT2ABACE1BACE2 | |
| SCHEMBL7048773 | 0.93 | DNM1 (0.54) | DNM1MEN1KMT2ACHRM2BCHE | |
| SCHEMBL7115591 | 0.91 | DNM1 (0.48) | DNM1MEN1KMT2ACHRM2MAOB | |
| SCHEMBL27593038 | 0.88 | DNM1 (0.55) | DNM1MEN1KMT2ACHRM2BCHE | |
| SCHEMBL7054663 | 0.88 | DNM1 (0.55) | DNM1MEN1KMT2ACHRM2BCHE | |
| SCHEMBL7053205 | 0.87 | DNM1 (0.49) | DNM1MEN1KMT2ACHRM2BCHE | |
| SCHEMBL7111374 | 0.87 | HTT (0.52) | DNM1MEN1KMT2ACHRM2BCHE | |
| SCHEMBL7055848 | 0.85 | DNM1 (0.49) | DNM1MEN1KMT2ACHRM2BCHE | |
| SCHEMBL7112618 | 0.85 | DNM1 (0.49) | DNM1MEN1KMT2ACHRM2BCHE | |
| SCHEMBL27576822 | 0.85 | DNM1 (0.49) | DNM1MEN1KMT2ACHRM2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |