Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883802 | 0.95 | FKBP1A (0.47) | FKBP1A | |
| SCHEMBL5492839 | 0.95 | FKBP1A (0.47) | FKBP1A | |
| SCHEMBL5497946 | 0.95 | FKBP1A (0.47) | FKBP1A | |
| SCHEMBL6877311 | 0.89 | ACE (0.52) | ACEACE2RAB9AFKBP1AREN | |
| SCHEMBL5495829 | 0.89 | ACE (0.52) | ACEACE2RAB9AFKBP1AREN | |
| SCHEMBL5495836 | 0.89 | ACE (0.52) | ACEACE2RAB9AFKBP1AREN | |
| SCHEMBL5497995 | 0.88 | FKBP1A (0.49) | ACEL3MBTL1ACE2FKBP1A | |
| SCHEMBL5497998 | 0.88 | FKBP1A (0.49) | ACEL3MBTL1ACE2FKBP1A | |
| SCHEMBL6883743 | 0.88 | FKBP1A (0.49) | ACEL3MBTL1ACE2FKBP1A | |
| SCHEMBL16116973 | 0.85 | SPHK1 (0.48) | ACEL3MBTL1ACE2FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458680-A1 | PRODRUGS TO D-PROLINES | F. Hoffmann-La Roche AG (CH) | 2004-09-22 | — | — | EP | claimed |
| WO-2003051836-A1 | PRODRUGS TO D-PROLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-26 | — | — | WO | claimed |