Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | VNN1 | O95497 | 13/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042081 | 0.88 | PTGS1 (0.51) | PTGS1KCNH2VNN1 | |
| SCHEMBL7044206 | 0.83 | PTGS1 (0.79) | PTGS1KCNH2VNN1 | |
| SCHEMBL7045821 | 0.83 | PTGS1 (0.79) | PTGS1KCNH2VNN1 | |
| SCHEMBL7045827 | 0.83 | PTGS1 (0.79) | PTGS1KCNH2VNN1 | |
| SCHEMBL7044200 | 0.83 | PTGS1 (0.79) | PTGS1KCNH2VNN1 | |
| SCHEMBL7044196 | 0.83 | PTGS1 (0.79) | PTGS1KCNH2VNN1 | |
| SCHEMBL22197940 | 0.83 | PTGS1 (0.57) | PTGS1KCNH2VNN1 | |
| SCHEMBL22170810 | 0.82 | PTGS1 (0.56) | PTGS1KCNH2VNN1 | |
| SCHEMBL28935014 | 0.82 | PTGS1 (0.56) | PTGS1KCNH2VNN1 | |
| SCHEMBL25759733 | 0.82 | PTGS1 (0.56) | PTGS1KCNH2VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030236213-A1 | Mimics of acyl coenzyme-A comprising pantolactone and pantothenic acid derivatives, compositions thereof, and methods of cholesterol management and related uses | ESPERION THERAPEUTICS | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236213-A1 | Mimics of acyl coenzyme-A comprising pantolactone and pantothenic acid derivatives, compositions thereof, and methods of cholesterol management and related uses | COASY, HMGCR, ACACA | PTGS1 507/4885KCNH2 3333/4885VNN1 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.