Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | S100A4 | P26447 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | USP8 | P40818 | 2/20 | 0.35 |
| ▸ | USP7 | Q93009 | 2/20 | 0.35 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30414425 | 0.86 | S100A4 (0.40) | EGFRS100A4CYP3A4TSHRMAPK1 | |
| SCHEMBL7049277 | 0.86 | S100A4 (0.40) | EGFRS100A4CYP3A4TSHRMAPK1 | |
| SCHEMBL21851280 | 0.86 | S100A4 (0.40) | EGFRS100A4GABRA1GABRG2GABRB3 | |
| SCHEMBL7047553 | 0.79 | EGFR (0.44) | EGFRUSP7USP47 | |
| SCHEMBL10018094 | 0.78 | S100A4 (0.32) | S100A4GABRA1GABRG2GABRB3GABRB1 | |
| SCHEMBL7045045 | 0.78 | MAPT (0.39) | EGFRGABRA1GABRG2GABRB3USP8 | |
| SCHEMBL7050692 | 0.78 | EGFR (0.38) | EGFRUSP8USP7USP47PDK2 | |
| SCHEMBL7044925 | 0.78 | EGFR (0.38) | EGFRS100A4CYP3A4TSHRMAPK1 | |
| SCHEMBL7046864 | 0.78 | EGFR (0.38) | EGFRS100A4PDK2METAP1ALDH1A1 | |
| SCHEMBL10049510 | 0.78 | EGFR (0.38) | EGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | disclosed |