SCHEMBL70495

SCHEMBL70495

CCCCc1ccc(O)c(Cl)c1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.56
ALOX5 P09917 2/20 0.44
HTT P42858 2/20 0.44
MEN1 O00255 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ELANE P08246 4/20 0.44
CTSG P08311 4/20 0.44
PRKCI P41743 1/20 0.43
CTRC Q99895 1/20 0.43
PTGS2 P35354 1/20 0.41
IAPP P10997 1/20 0.39
NPC1 O15118 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706286 0.83 TYR (0.54) TYRALOX5HTTMEN1TP53
SCHEMBL2382145 0.82 TYR (0.61) TYRALOX5HTTMEN1TP53
SCHEMBL982811 0.81 TYR (0.59) TYRALOX5HTTMEN1TP53
SCHEMBL8734971 0.81 TYR (0.47) TYRALOX5HTTMEN1TP53
SCHEMBL9717548 0.81 TYR (0.56) TYRALOX5HTTMEN1TP53
SCHEMBL16190919 0.78 TYR (0.86) TYRALOX5HTTMEN1TP53
SCHEMBL10355484 0.78 TYR (0.62) TYRALOX5HTTMEN1TP53
SCHEMBL6229740 0.78 TYR (0.49) TYRALOX5HTTMEN1TP53
SCHEMBL11866128 0.78 TYR (0.62) TYRALOX5HTTMEN1TP53
SCHEMBL5678235 0.77 TYR (0.66) TYRALOX5HTTMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TYR 134/4885ALOX5 899/4885HTT 1871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.