Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70495 | 0.83 | TYR (0.56) | TYRHTTMEN1TP53CYP3A4 | |
| SCHEMBL5886405 | 0.82 | TYR (0.65) | TYRHTTMEN1TP53CYP3A4 | |
| SCHEMBL8089662 | 0.81 | CTRC (0.44) | TYRHTTMEN1TP53CYP3A4 | |
| SCHEMBL10157301 | 0.81 | CTRC (0.49) | TYRHTTMEN1TP53CYP3A4 | |
| SCHEMBL14824915 | 0.81 | CTRC (0.44) | TYRHTTMEN1TP53CYP3A4 | |
| SCHEMBL5676330 | 0.81 | TYR (0.62) | TYRHTTMEN1TP53CYP3A4 | |
| SCHEMBL709628 | 0.81 | TYR (0.58) | TYRHTTMEN1TP53CYP3A4 | |
| SCHEMBL11866128 | 0.80 | TYR (0.62) | TYRHTTMEN1TP53CYP3A4 | |
| SCHEMBL9717548 | 0.79 | TYR (0.56) | TYRHTTMEN1TP53CYP3A4 | |
| SCHEMBL28796605 | 0.78 | TYR (0.54) | TYRHTTMEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992010992-A1 | ORAL COMPOSITIONS EFFECTIVE AGAINST PLAQUE AND GINGIVITIS | THE PROCTER & GAMBLE COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |