Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12603818 | 0.87 | MAOB (0.43) | MAOBMAOAALDH1A1HPGDMAPT | |
| SCHEMBL3069277 | 0.81 | PDCD1 (0.46) | MAOBMAOAALDH1A1HPGDMAPT | |
| SCHEMBL6851708 | 0.79 | MAOB (0.40) | MAOBMAOAALDH1A1HPGDMAPT | |
| SCHEMBL13744619 | 0.77 | PTGER4 (0.46) | MAOBMAOAALDH1A1HPGDMAPT | |
| SCHEMBL15986389 | 0.77 | PTGER4 (0.43) | MAOBMAOAALDH1A1HPGDMAPT | |
| SCHEMBL347966 | 0.74 | MAOB (0.53) | MAOBMAOAALDH1A1HPGDMAPT | |
| SCHEMBL3878829 | 0.72 | NPC1 (0.52) | MAOBMAOAALDH1A1HPGDMAPT | |
| SCHEMBL10205942 | 0.72 | MAOB (0.47) | MAOBMAOAALDH1A1HPGDMAPT | |
| SCHEMBL13791218 | 0.72 | CSNK2A2 (0.46) | MAOBALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL4348247 | 0.72 | KDM4E (0.50) | MAOBMAOAALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | claimed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |