SCHEMBL7049690

SCHEMBL7049690

[Li]CCCO[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8412779 0.91
SCHEMBL8412773 0.88
SCHEMBL3044372 0.88
SCHEMBL7045195 0.88
SCHEMBL823000 0.83
SCHEMBL16295146 0.80
SCHEMBL9284273 0.80
SCHEMBL16294338 0.80
SCHEMBL20483089 0.80
SCHEMBL1223591 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030114611-A1 Functionalized alkyllithium formulations with improved thermal stability and processes for making the same FMC CORPORATION 2003-06-19 US claimed
US-20030114592-A1 Processes for improving stability of living polymer chain ends FMC CORPORATION 2003-06-19 US claimed
US-5912378-A Process for preparing trimethylsilyloxy functionalized alkyllithium compounds FMC CORPORATION (US) 1999-06-15 US claimed
EP-0800525-A1 PROCESS FOR PREPARING TRIMETHYLSILYLOXY FUNCTIONALIZED ALKYLLITHIUM COMPOUNDS FMC CORPORATION (US) 1997-10-15 EP claimed
EP-0800525-A4 1997-10-15 EP claimed
WO-1996003408-A1 PROCESS FOR PREPARING TRIMETHYLSILYLOXY FUNCTIONALIZED ALKYLLITHIUM COMPOUNDS FMC CORPORATION (US) 1996-02-08 WO claimed
US-20030114611-A1 Functionalized alkyllithium formulations with improved thermal stability and processes for making the same FMC CORPORATION 2003-06-19 US disclosed
US-20030114592-A1 Processes for improving stability of living polymer chain ends FMC CORPORATION 2003-06-19 US disclosed
EP-0800525-B1 PROCESS FOR PREPARING TRIMETHYLSILYLOXY FUNCTIONALIZED ALKYLLITHIUM COMPOUNDS FMC CORP (US) 2003-04-09 EP disclosed
EP-0675140-B1 Protected functional initiators for making terminally functionalized polymers SHELL INT RESEARCH (NL) 2000-08-09 EP disclosed
US-5912378-A Process for preparing trimethylsilyloxy functionalized alkyllithium compounds FMC CORPORATION (US) 1999-06-15 US disclosed
EP-0675140-A1 Protected functional initiators for making terminally functionalized polymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1995-10-04 EP disclosed
US-5416168-A Polybutadiene, lithium catalyst and ethylene oxide terminator and hydrogenation SHELL OIL COMPANY (US) 1995-05-16 US disclosed
US-5403946-A Process of preparing trimethylsilyloxy functionalized alkyllithium compounds FMC CORPORATION (US) 1995-04-04 US disclosed