SCHEMBL7050000

SCHEMBL7050000

N#CC1=C(c2cccc3ccccc23)CN(C(=O)CNCc2ccc(C#N)cc2)CC1

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 18/20 0.63
FNTB P49356 18/20 0.63
PGGT1B P53609 11/20 0.63
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7047035 0.78 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7047031 0.77 FNTA (0.65) FNTAFNTBPGGT1B
SCHEMBL7050845 0.75 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7049991 0.74 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7047026 0.74 FNTA (0.54) FNTAFNTBPGGT1B
SCHEMBL7051608 0.72 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7048886 0.69 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7047915 0.68 FNTA (0.48) FNTAFNTBPGGT1BRAB9A
SCHEMBL7053273 0.68 FNTA (0.49) FNTAFNTBPGGT1B
SCHEMBL7046920 0.67 FNTA (0.73) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030216441-A1 Farnesyltransferase inhibitors WEINSTOCK, STEVEN F. 2003-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216441-A1 Farnesyltransferase inhibitors FNTA, FNTB, LCAT FNTA 1/4885FNTB 2/4885PGGT1B 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.