SCHEMBL7050845

SCHEMBL7050845

Cn1cncc1C[C@@H](NCc1ccc(C#N)cc1)C(=O)N1CCC(C#N)=C(c2cccc3ccccc23)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 19/20 1.00
FNTB P49356 19/20 1.00
PGGT1B P53609 12/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7048886 0.85 FNTA (1.00) FNTAFNTBPGGT1B
Hydrochloric Acid SCHEMBL7048907 0.83 FNTA (0.70) FNTAFNTBPGGT1B
SCHEMBL7051608 0.81 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7049991 0.80 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7047035 0.76 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7050000 0.75 FNTA (0.63) FNTAFNTBPGGT1B
SCHEMBL7054747 0.75 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7050761 0.73 FNTA (0.55) FNTAFNTBPGGT1B
SCHEMBL7052611 0.73 FNTA (0.62) FNTAFNTBPGGT1B
SCHEMBL7046915 0.70 FNTA (1.00) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030216441-A1 Farnesyltransferase inhibitors WEINSTOCK, STEVEN F. 2003-11-20 US claimed
US-20030216441-A1 Farnesyltransferase inhibitors WEINSTOCK, STEVEN F. 2003-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216441-A1 Farnesyltransferase inhibitors FNTA, FNTB, LCAT FNTA 1/4885FNTB 2/4885PGGT1B 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.