Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.76 |
| ▸ | PTPRA | P18433 | 8/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.56 |
| ▸ | PTPRF | P10586 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491797 | 0.86 | PTPN1 (1.00) | PTPN1PTPRAPTPN2PTPRF | |
| SCHEMBL6504689 | 0.85 | PTPN1 (1.00) | PTPN1PTPRAPTPN2PTPRF | |
| SCHEMBL6533772 | 0.81 | PTPN1 (1.00) | PTPN1PTPRAPTPN2PTPRF | |
| SCHEMBL6501815 | 0.74 | PTPN1 (0.83) | PTPN1PTPRAPTPN2PTPRF | |
| SCHEMBL6499405 | 0.72 | PTPN1 (1.00) | PTPN1PTPRAPTPN2PTPRF | |
| SCHEMBL6500760 | 0.72 | PTPN1 (1.00) | PTPN1PTPRAPTPN2PTPRF | |
| SCHEMBL6504066 | 0.72 | PTPN1 (0.85) | PTPN1PTPRAPTPN2PTPRF | |
| SCHEMBL6492839 | 0.70 | PTPN1 (0.74) | PTPN1PTPRAPTPN2PTPRF | |
| SCHEMBL6500588 | 0.68 | PTPN1 (1.00) | PTPN1PTPRAPTPN2PTPRF | |
| SCHEMBL7254530 | 0.67 | PTPN1 (0.78) | PTPN1PTPRAPTPN2PTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003020688-A1 | SELECTIVE PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-03-13 | — | — | WO | claimed |