Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.69 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.69 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.69 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047631 | 0.97 | PTGIR (0.74) | PTGIRPTGDRPTGER1PTGER3LMNA | |
| SCHEMBL7054735 | 0.95 | PTGIR (0.65) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7776656 | 0.93 | PTGIR (0.80) | PTGIRPTGDRPTGER1PTGER3LMNA | |
| SCHEMBL7778514 | 0.93 | PTGIR (0.80) | PTGIRPTGDRPTGER1PTGER3LMNA | |
| SCHEMBL7778523 | 0.93 | PTGIR (0.80) | PTGIRPTGDRPTGER1PTGER3LMNA | |
| SCHEMBL7051528 | 0.93 | PTGIR (0.62) | PTGIRPTGDRPTGER1PTGER3LMNA | |
| SCHEMBL7054777 | 0.92 | PTGIR (0.66) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7748560 | 0.92 | PTGIR (0.66) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7050461 | 0.90 | PTGIR (0.73) | PTGIRPTGDRPTGER1PTGER3LMNA | |
| SCHEMBL7050802 | 0.89 | PTGIR (0.87) | PTGIRPTGDRPTGER1PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042277-B1 | NAPHTHALENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6303649-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTERIAL OBSTRUCTION, CEREBROVASCULAR DISEASE, HEPATIC CIRRHOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASE, RESTENOSIS, ISCHEMIC COMPLICATIONS AFTER CORONARY ANGIOPLASTY, HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-16 | — | — | US | disclosed |
| EP-1042277-A1 | NAPHTHALENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999032435-A1 | NAPHTHALENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |