Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.62 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.62 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.62 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153256 | 0.94 | PTGIR (0.61) | PTGIRPTGER1PTGER3PTGDRRAB9A | |
| SCHEMBL7050841 | 0.93 | PTGIR (0.69) | PTGIRPTGER1PTGER3PTGDRLMNA | |
| SCHEMBL7047631 | 0.92 | PTGIR (0.74) | PTGIRPTGER1PTGER3PTGDRLMNA | |
| SCHEMBL7050867 | 0.90 | PTGIR (0.77) | PTGIRPTGER1PTGER3PTGDRAGTR2 | |
| SCHEMBL7054735 | 0.88 | PTGIR (0.65) | PTGIRPTGER1PTGER3PTGDR | |
| SCHEMBL7776656 | 0.87 | PTGIR (0.80) | PTGIRPTGER1PTGER3PTGDRRAB9A | |
| SCHEMBL7778523 | 0.87 | PTGIR (0.80) | PTGIRPTGER1PTGER3PTGDRRAB9A | |
| SCHEMBL7778514 | 0.87 | PTGIR (0.80) | PTGIRPTGER1PTGER3PTGDRRAB9A | |
| SCHEMBL7748560 | 0.85 | PTGIR (0.66) | PTGIRPTGER1PTGER3PTGDR | |
| SCHEMBL7054777 | 0.85 | PTGIR (0.66) | PTGIRPTGER1PTGER3PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042277-B1 | NAPHTHALENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6303649-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTERIAL OBSTRUCTION, CEREBROVASCULAR DISEASE, HEPATIC CIRRHOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASE, RESTENOSIS, ISCHEMIC COMPLICATIONS AFTER CORONARY ANGIOPLASTY, HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-16 | — | — | US | disclosed |