SCHEMBL7051131

SCHEMBL7051131

ONCCc1c[nH]c2c1CCC=C2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14300543 0.79 HTR2A (0.35)
SCHEMBL19114440 0.73 BUB1 (0.34)
SCHEMBL13542070 0.65
SCHEMBL16181722 0.65
SCHEMBL20221708 0.61
SCHEMBL16622953 0.56 HTR2C (0.33)
SCHEMBL19593972 0.54 HSD17B10 (0.30)
SCHEMBL13488455 0.53 HTR2A (0.35)
SCHEMBL15630267 0.52
SCHEMBL14068308 0.52 HTR1A (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1310250-A1 Use of the compound 2-methoxyphenyl-1-methyl-5P-methylbenzoyl-pyrrol-2-acetamido acetate for the production of an antiinflammatory drug with prevention of gastric hypersecretion and renal impairment MEDOSAN RICERCA S.r.l. (IT) 2003-05-14 EP disclosed
EP-1024807-B1 USE OF THE COMPOUND 2-METHOXYPHENYL-1-METHYL-5P-METHYLBENZOYL-PYRROL-2-ACETAMIDO ACETATE FOR THE PRODUCTION OF AN ANTI-INFLAMMATORY DRUG WITH PREVENTION OF GASTRIC HYPERSECRETION AND RENAL IMPAIRMENT MEDOSAN RICERCA SRL (IT) 2003-04-16 EP disclosed
US-6180658-B1 ADMINISTERING 2-METHOXYPHENYL-1-METHYL-5-P-METHYLBENZOYLPYRROLE-2-ACETAMIDEA CETATE MEDOSAN RICERCA S.R.L. (IT) 2001-01-30 US disclosed
EP-1024807-A1 USE OF THE COMPOUND 2-METHOXYPHENYL-1-METHYL-5P-METHYLBENZOYL-PYRROL-2-ACETAMIDO ACETATE FOR THE PRODUCTION OF AN ANTI-INFLAMMATORY DRUG WITH PREVENTION OF GASTRIC HYPERSECRETION AND RENAL IMPAIRMENT MEDOSAN RICERCA S.r.l. (IT) 2000-08-09 EP disclosed
US-5889041-A ADMINISTERING AMTOLMETIN GUACIL MEDOSAN RICERCA S.R.L. (IT) 1999-03-30 US disclosed
WO-1999007363-A1 USE OF THE COMPOUND 2-METHOXYPHENYL-1-METHYL-5P-METHYLBENZOYL-PYRROL-2-ACETAMIDO ACETATE FOR THE PRODUCTION OF AN ANTI-INFLAMMATORY DRUG WITH PREVENTION OF GASTRIC HYPERSECRETION AND RENAL IMPAIRMENT MEDOSAN, RICERCA S.R.L. (IT) 1999-02-18 WO disclosed