SCHEMBL7051144

SCHEMBL7051144

CCC(C)Cc1cccc(-c2ccccc2)c1C#N

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 15/20 0.45
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPK1 P28482 1/20 0.43
GRM2 Q14416 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
PDCD1 Q15116 1/20 0.38
SQOR Q9Y6N5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10601749 0.81 KMT2A (0.55) CD274PDCD1
SCHEMBL29210714 0.78 KDM4E (0.47) CD274KDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL30777434 0.78 CD274 (0.45) CD274KDM4EALDH1A1MAPK1GRM2
SCHEMBL588693 0.78 CD274 (0.45) CD274KDM4EALDH1A1MAPK1GRM2
SCHEMBL14798543 0.78 GRM2 (0.51) CD274KDM4EALDH1A1MAPK1GRM2
SCHEMBL10590473 0.78 CYP11B2 (0.39)
SCHEMBL16554640 0.76 CD274 (0.55) CD274KDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL27569853 0.76 CD274 (0.44) CD274KDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL31364597 0.75 PTGDR2 (0.40) KDM4EALDH1A1SQOR
SCHEMBL10590479 0.75 PTGDR2 (0.40) KDM4EALDH1A1SQOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0193401-B1 Projection type liquid crystal display device FUJITSU LTD (JP) 2003-04-23 EP disclosed
US-4812034-A Projection type liquid crystal display device FUJITSU LIMITED (JP) 1989-03-14 US disclosed
EP-0193401-A2 Projection type liquid crystal display device FUJITSU LIMITED (JP) 1986-09-03 EP disclosed