Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 10/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | STK10 | O94804 | 2/20 | 0.32 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051497 | 1.00 | CES1 (0.45) | CES1HTR2CTGM2CSF1RDNMT1 | |
| SCHEMBL7049797 | 0.89 | CES1 (0.45) | CES1HTR2CTGM2CSF1RDNMT1 | |
| SCHEMBL7049799 | 0.89 | CES1 (0.45) | CES1HTR2CTGM2CSF1RDNMT1 | |
| SCHEMBL7053293 | 0.84 | CES1 (0.35) | CES1TGM2AR | |
| SCHEMBL7053299 | 0.84 | CES1 (0.35) | CES1TGM2AR | |
| SCHEMBL7049842 | 0.84 | CES1 (0.65) | CES1TGM2DNMT1KDRNSD2 | |
| SCHEMBL7049846 | 0.84 | CES1 (0.65) | CES1TGM2DNMT1KDRNSD2 | |
| SCHEMBL7049368 | 0.83 | CES1 (0.41) | CES1TGM2BCHE | |
| SCHEMBL7049364 | 0.83 | CES1 (0.41) | CES1TGM2BCHE | |
| SCHEMBL7053901 | 0.81 | CES1 (0.38) | CES1HTR2CTGM2CSF1RFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706396-B1 | 1,2,3,4-TETRAHYDROQUINOLINE-2,3,4-TRIONE-3 OR 4-OXIMES AND USE | OREGON STATE (US) | 2003-05-02 | — | — | EP | disclosed |
| US-5652368-A | NERVOUS SYSTEM DISORDERS, ALZHEIMER'S DISEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-07-29 | — | — | US | disclosed |
| US-5475007-A | Preventing convulsions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-12-12 | — | — | US | disclosed |