SCHEMBL7051615

SCHEMBL7051615

CCCCCCCCCCC(OC(C)C)C(=O)O[SiH3]

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 5/20 0.43
FFAR1 O14842 1/20 0.43
ZDHHC7 Q9NXF8 1/20 0.42
LMNA P02545 2/20 0.41
FAAH O00519 1/20 0.41
ACE2 Q9BYF1 1/20 0.40
CA1 P00915 2/20 0.39
MAPT P10636 2/20 0.38
LCK P06239 1/20 0.38
PPARD Q03181 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
ABCB1 P08183 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7060613 1.00 GPR84 (0.43) GPR84FFAR1ZDHHC7LMNAFAAH
SCHEMBL19447340 0.84 ZDHHC7 (0.56) GPR84FFAR1ZDHHC7LMNAFAAH
SCHEMBL27670297 0.82 GPR84 (0.53) GPR84FFAR1LMNAACE2CA1
SCHEMBL29165517 0.82 GPR84 (0.53) GPR84FFAR1LMNAACE2CA1
SCHEMBL7060129 0.81 GPR84 (0.44) GPR84FFAR1ZDHHC7FAAHACE2
SCHEMBL7058909 0.81 GPR84 (0.44) GPR84FFAR1ZDHHC7FAAHACE2
SCHEMBL27497981 0.80 GPR84 (0.52) GPR84FFAR1LMNAACE2CA1
SCHEMBL27523512 0.80 GPR84 (0.52) GPR84FFAR1LMNAACE2CA1
SCHEMBL27335805 0.80 GPR84 (0.52) GPR84FFAR1LMNAACE2CA1
SCHEMBL27525393 0.80 GPR84 (0.52) GPR84FFAR1LMNAACE2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006118-B1 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond DOW CORNING ASIA LTD (JP) 2003-05-07 EP disclosed
US-6175031-B1 PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE DOW CORNING ASIA, LTD. (JP) 2001-01-16 US disclosed
US-6111126-A Method for synthesizing organosilicon compounds that contain a functional group bonded to silicon across the Si-C bond DOW CORNING ASIA, LTD. (JP) 2000-08-29 US disclosed
EP-1006118-A2 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond Dow Corning Asia, Ltd. (JP) 2000-06-07 EP disclosed