Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 1.00 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | F13A1 | P00488 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1460951 | 1.00 | TBXAS1 (1.00) | TBXAS1TERTF13A1MAPTRXFP1 | |
| SCHEMBL11009198 | 1.00 | TBXAS1 (1.00) | TBXAS1TERTF13A1MAPTRXFP1 | |
| SCHEMBL1091991 | 1.00 | TBXAS1 (1.00) | TBXAS1TERTF13A1MAPTRXFP1 | |
| SCHEMBL28703772 | 1.00 | TBXAS1 (1.00) | TBXAS1TERTF13A1MAPTRXFP1 | |
| SCHEMBL4655987 | 0.98 | TBXAS1 (0.97) | TBXAS1TERTF13A1MAPTRXFP1 | |
| SCHEMBL8979265 | 0.93 | TBXAS1 (0.87) | TBXAS1TERTMAPT | |
| Adipic Acid SCHEMBL2459217 | 0.92 | TBXAS1 (0.85) | TBXAS1TSHR | |
| Hydrochloric Acid SCHEMBL11657876 | 0.91 | TBXAS1 (0.87) | TBXAS1TERTMAPT | |
| SCHEMBL30917328 | 0.91 | TBXAS1 (0.83) | TBXAS1TERTMAPTLMNATSHR | |
| Thiophene SCHEMBL8576663 | 0.88 | TBXAS1 (0.78) | TBXAS1TERTMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003022214-A2 | PIPERAZINE AND HOMOPIPERAZINE COMPOUNDS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-03-20 | — | — | WO | disclosed |
| US-4444775-A | ENZYME INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1984-04-24 | — | — | US | disclosed |