Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 5/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049670 | 0.93 | SRC (0.42) | L3MBTL1KMT2APLGKLKB1SRC | |
| SCHEMBL7052132 | 0.88 | L3MBTL1 (0.42) | L3MBTL1TP53KMT2APLGKLKB1 | |
| SCHEMBL4650317 | 0.84 | KMT2A (0.41) | L3MBTL1KMT2APLGKLKB1SRC | |
| SCHEMBL7049668 | 0.80 | SRC (0.45) | L3MBTL1KMT2APLGSRCGRIA1 | |
| SCHEMBL7049667 | 0.78 | SRC (0.42) | L3MBTL1KMT2APLGKLKB1SRC | |
| SCHEMBL4650324 | 0.77 | KMT2A (0.44) | L3MBTL1KMT2APLGSRCGRIA1 | |
| SCHEMBL4650362 | 0.73 | GRIA1 (0.55) | L3MBTL1KMT2ASRCGRIA1CTSL | |
| SCHEMBL4650855 | 0.73 | KMT2A (0.47) | L3MBTL1KMT2APLGSRCGRIA1 | |
| SCHEMBL14066218 | 0.70 | SRC (0.48) | L3MBTL1KMT2ASRCGRIA1CTSL | |
| SCHEMBL4651392 | 0.69 | GRIA1 (0.73) | L3MBTL1KMT2AGRIA1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301474-A2 | TYROSINE DERIVATIVES AS PHOSPHATASE INHIBITORS | Array Biopharma Inc. (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004412-A2 | TYROSINE DERIVATIVES AS PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2002-01-17 | — | — | WO | disclosed |