Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052157 | 1.00 | CA1 (0.33) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL7053698 | 0.90 | CA1 (0.33) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL7056832 | 0.90 | CAPN9 (0.35) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL7056828 | 0.90 | CAPN9 (0.35) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL7053697 | 0.90 | CA1 (0.33) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL8873553 | 0.86 | CA1 (0.33) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL8873548 | 0.86 | CA1 (0.33) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL8875193 | 0.83 | CAPN9 (0.34) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL8875196 | 0.83 | CAPN9 (0.34) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL7053822 | 0.82 | CCNB2 (0.35) | ALDH1A1POLBGAAMAPTMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706396-B1 | 1,2,3,4-TETRAHYDROQUINOLINE-2,3,4-TRIONE-3 OR 4-OXIMES AND USE | OREGON STATE (US) | 2003-05-02 | — | — | EP | disclosed |
| US-5652368-A | NERVOUS SYSTEM DISORDERS, ALZHEIMER'S DISEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-07-29 | — | — | US | disclosed |
| US-5475007-A | Preventing convulsions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-12-12 | — | — | US | disclosed |