Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.64 |
| ▸ | DRD3 | P35462 | 9/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053695 | 0.84 | DRD3 (0.81) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL7055557 | 0.80 | DRD3 (0.58) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL7056439 | 0.80 | DRD2 (0.76) | DRD2DRD3DRD4ADRA1A | |
| SCHEMBL7049959 | 0.78 | DRD2 (0.61) | DRD2DRD3DRD4ADRA1A | |
| SCHEMBL7055031 | 0.78 | DRD2 (0.64) | DRD2DRD3DRD4ADRA1A | |
| SCHEMBL12406090 | 0.76 | DRD3 (0.78) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL29730963 | 0.73 | DRD3 (1.00) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL7052921 | 0.73 | DRD2 (0.70) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL7057153 | 0.73 | CCR3 (0.54) | DRD2DRD3ADRA1A | |
| SCHEMBL10724181 | 0.72 | DRD2 (0.75) | DRD2DRD3HTR1ADRD4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028728-A1 | 4-(4-SUBSTITUTED PIPERAZINYL-1YL)-BUTYLCARBOXAMIDES AS D3 DOPAMINE SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |