Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 20/20 | 0.82 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.82 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.82 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.82 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052341 | 0.97 | PTGIR (0.81) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7050827 | 0.92 | PTGIR (0.91) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7050802 | 0.92 | PTGIR (0.87) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL6612991 | 0.90 | PTGIR (1.00) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL6612986 | 0.90 | PTGIR (1.00) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL29760759 | 0.90 | PTGIR (1.00) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7778677 | 0.90 | PTGIR (1.00) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7748560 | 0.89 | PTGIR (0.66) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7054777 | 0.89 | PTGIR (0.66) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7052038 | 0.87 | PTGIR (0.86) | PTGIRPTGDRPTGER3PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042277-B1 | NAPHTHALENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6303649-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTERIAL OBSTRUCTION, CEREBROVASCULAR DISEASE, HEPATIC CIRRHOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASE, RESTENOSIS, ISCHEMIC COMPLICATIONS AFTER CORONARY ANGIOPLASTY, HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-16 | — | — | US | disclosed |