Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 19/20 | 1.00 |
| ▸ | PTGDR | Q13258 | 5/20 | 1.00 |
| ▸ | PTGER3 | P43115 | 2/20 | 1.00 |
| ▸ | PTGER1 | P34995 | 1/20 | 1.00 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29760759 | 1.00 | PTGIR (1.00) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL6612986 | 1.00 | PTGIR (1.00) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL6612991 | 1.00 | PTGIR (1.00) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7051509 | 0.95 | PTGIR (0.91) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7050827 | 0.95 | PTGIR (0.91) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7713237 | 0.95 | PTGIR (0.90) | PTGIRPTGDRPTGER3PTGER1 | |
| SCHEMBL7048691 | 0.94 | PTGIR (0.89) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7050802 | 0.93 | PTGIR (0.87) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7052038 | 0.93 | PTGIR (0.86) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7052364 | 0.90 | PTGIR (0.82) | PTGIRPTGDRPTGER3PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | claimed |
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |