Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 18/20 | 0.49 |
| ▸ | MAP2K2 | P36507 | 5/20 | 0.41 |
| ▸ | MAP2K5 | Q13163 | 2/20 | 0.40 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7159175 | 0.90 | MAP2K1 (0.53) | MAP2K1MAP2K2MAP2K5EIF2AK1PIM1 | |
| SCHEMBL4851711 | 0.90 | MAP2K1 (0.59) | MAP2K1MAP2K2MAP2K5EIF2AK1MEN1 | |
| SCHEMBL4860711 | 0.89 | MAP2K1 (0.60) | MAP2K1MAP2K2MAP2K5EIF2AK1MEN1 | |
| SCHEMBL4863465 | 0.89 | MAP2K1 (0.60) | MAP2K1MAP2K2MAP2K5EIF2AK1MEN1 | |
| SCHEMBL7050219 | 0.88 | MAP2K1 (0.42) | MAP2K1MAP2K2MAP2K5EIF2AK1MEN1 | |
| SCHEMBL7047956 | 0.87 | MAP2K1 (0.43) | MAP2K1MAP2K2PIM1CAMK2BCYP3A4 | |
| SCHEMBL6295247 | 0.87 | MAP2K1 (0.47) | MAP2K1MAP2K2MAP2K5EIF2AK1MEN1 | |
| SCHEMBL7047882 | 0.84 | MAP2K1 (0.45) | MAP2K1MAP2K2MAP2K5EIF2AK1MEN1 | |
| SCHEMBL4851949 | 0.84 | MAP2K1 (0.60) | MAP2K1MAP2K2MAP2K5EIF2AK1MEN1 | |
| SCHEMBL4858026 | 0.83 | MAP2K1 (0.60) | MAP2K1MAP2K2MAP2K5EIF2AK1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |