Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 19/20 | 0.53 |
| ▸ | MAP2K2 | P36507 | 5/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAP2K5 | Q13163 | 2/20 | 0.45 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858026 | 0.93 | MAP2K1 (0.60) | MAP2K1MAP2K2PIM1CAMK2BMAP2K5 | |
| SCHEMBL4859846 | 0.93 | MAP2K1 (0.60) | MAP2K1MAP2K2PIM1CAMK2BCYP3A4 | |
| SCHEMBL7047956 | 0.91 | MAP2K1 (0.43) | MAP2K1MAP2K2PIM1CAMK2BCYP3A4 | |
| SCHEMBL7052404 | 0.90 | MAP2K1 (0.49) | MAP2K1MAP2K2PIM1CAMK2BCYP3A4 | |
| SCHEMBL7050032 | 0.88 | MAP2K1 (0.47) | MAP2K1MAP2K2PIM1CAMK2BMAP2K5 | |
| SCHEMBL4863738 | 0.85 | MAP2K1 (0.62) | MAP2K1MAP2K2PIM1CAMK2BMAP2K5 | |
| SCHEMBL4860711 | 0.84 | MAP2K1 (0.60) | MAP2K1MAP2K2PIM1CAMK2BCYP3A4 | |
| SCHEMBL4863465 | 0.84 | MAP2K1 (0.60) | MAP2K1MAP2K2PIM1CAMK2BMAP2K5 | |
| SCHEMBL6295247 | 0.84 | MAP2K1 (0.47) | MAP2K1MAP2K2PIM1CAMK2BMAP2K5 | |
| SCHEMBL4858354 | 0.83 | MAP2K1 (0.48) | MAP2K1MAP2K2PIM1CAMK2BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |