Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 18/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854971 | 0.97 | MAP2K1 (0.62) | MAP2K1MEN1KMT2ATDP1MAP2K2 | |
| SCHEMBL4854581 | 0.93 | MAP2K1 (0.61) | MAP2K1MEN1KMT2ATDP1MAP2K2 | |
| SCHEMBL7053952 | 0.91 | MAP2K1 (0.62) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL7056183 | 0.90 | MEN1 (0.70) | MAP2K1MEN1KMT2ATDP1MAP2K2 | |
| Benzamide SCHEMBL7053687 | 0.90 | MAP2K1 (0.54) | MAP2K1MEN1KMT2ATDP1MAP2K2 | |
| SCHEMBL4857428 | 0.89 | MEN1 (0.60) | MAP2K1MEN1KMT2ATDP1MAP2K2 | |
| SCHEMBL7050814 | 0.89 | MAP2K1 (0.59) | MAP2K1MEN1KMT2ATDP1MAP2K2 | |
| SCHEMBL4863745 | 0.87 | MEN1 (0.71) | MAP2K1MEN1KMT2ATDP1MAP2K2 | |
| SCHEMBL4861756 | 0.87 | MAP2K1 (0.76) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL4864347 | 0.87 | MEN1 (0.58) | MAP2K1MEN1KMT2ATDP1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |