Sugi Predict

Sugi Predict / Compounds / Benzamide

Benzamide

Benzamide

SCHEMBL7053687

Cc1cc(I)ccc1Nc1c(C(=O)NOCCCO)cc(Cl)c(F)c1F.NC(=O)c1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MAP2K1 Q02750 19/20 0.54
▸ MEN1 O00255 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ TDP1 Q9NUW8 1/20 0.51
▸ MAP2K2 P36507 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4854971 0.92 MAP2K1 (0.62) MAP2K1MEN1KMT2ATDP1MAP2K2
SCHEMBL7052569 0.90 MAP2K1 (0.59) MAP2K1MEN1KMT2ATDP1MAP2K2
SCHEMBL4854581 0.87 MAP2K1 (0.61) MAP2K1MEN1KMT2ATDP1MAP2K2
Benzamide SCHEMBL7051425 0.87 MEN1 (0.51) MAP2K1MEN1KMT2ATDP1MAP2K2
Benzamide SCHEMBL7052142 0.85 MAP2K1 (0.54) MAP2K1MAP2K2
SCHEMBL4863745 0.83 MEN1 (0.71) MAP2K1MEN1KMT2ATDP1MAP2K2
SCHEMBL4857428 0.83 MEN1 (0.60) MAP2K1MEN1KMT2ATDP1MAP2K2
SCHEMBL4861756 0.83 MAP2K1 (0.76) MAP2K1MAP2K2
Benzamide SCHEMBL7052137 0.82 MEN1 (0.53) MAP2K1MEN1KMT2ATDP1MAP2K2
SCHEMBL7055347 0.82 MAP2K1 (0.75) MAP2K1MAP2K2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1301472-A2 OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS WARNER-LAMBERT COMPANY (US) 2003-04-16 — — EP claimed
WO-2002006213-A2 OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS WARNER-LAMBERT COMPANY (US) 2002-01-24 — — WO claimed