SCHEMBL705283

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10115731	0.82	MAPT (0.52)	HTTMAPTTGM2KEAP1NFE2L2
	SCHEMBL10110708	0.81	SLC2A1 (0.52)	HTTMAPTTGM2KEAP1NFE2L2
	SCHEMBL10110709	0.80	HTT (0.55)	HTTMAPTTGM2KEAP1NFE2L2
	SCHEMBL709448	0.79	HTT (0.45)	HTTMAPTTGM2KEAP1NFE2L2
	SCHEMBL707237	0.79	HTT (0.56)	HTTTGM2KEAP1NFE2L2LMNA
	SCHEMBL707615	0.77	HTT (0.46)	HTTTGM2KEAP1NFE2L2LMNA
	SCHEMBL10115813	0.77	HTT (0.46)	HTTMAPTTGM2KEAP1NFE2L2
	SCHEMBL15834318	0.76	HTT (0.50)	HTTTGM2KEAP1NFE2L2LMNA
	SCHEMBL1895297	0.75	HTT (0.58)	HTTMAPTTGM2KEAP1NFE2L2
	SCHEMBL6240402	0.74	HTT (0.56)	HTTMAPTTGM2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.