Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10633132 | 0.85 | MAPK1 (0.42) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL8741645 | 0.82 | MAPK1 (0.44) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL22730167 | 0.81 | MAPK1 (0.39) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL6404472 | 0.80 | ALDH1A1 (0.44) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL10630507 | 0.79 | MAPK1 (0.38) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL9210673 | 0.79 | MAPK1 (0.46) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL10633204 | 0.79 | TAAR1 (0.48) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL8741597 | 0.78 | MAPK1 (0.41) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL8741710 | 0.78 | MAPK1 (0.41) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL10628304 | 0.78 | TAAR1 (0.39) | ALDH1A1ALOX15ESR1ESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4748262-A | (Phenyl dimethyl carbinyl) silane compound and a method for the preparation thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-05-31 | — | — | US | claimed |
| JP-2042088-A | — | — | None | — | — | JP | disclosed |
| JP-63063683-A | — | — | None | — | — | JP | disclosed |
| EP-2468798-B1 | SOLID ELECTROLYTE MEMBRANE FOR FUEL CELL AND PROCESS FOR PRODUCING SAME | CENTRAL GLASS CO LTD (JP) | 2017-03-08 | — | — | EP | disclosed |
| US-8445551-B2 | Solid electrolyte membrane for fuel cell and process for producing same | CENTRAL GLASS COMPANY, LTD. (JP) | 2013-05-21 | — | — | US | disclosed |
| EP-2468798-A1 | SOLID ELECTROLYTE MEMBRANE FOR FUEL CELL AND PROCESS FOR PRODUCING SAME | Central Glass Company, Limited (JP) | 2012-06-27 | — | — | EP | disclosed |
| US-20120142791-A1 | Solid Electrolyte Membrane for Fuel Cell and Process for Producing Same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| EP-0985674-B1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS | MITSUBISHI CHEM CORP (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6255515-B1 | COORDINATION POLYMERIZATION CATALYSTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-03 | — | — | US | disclosed |
| US-6156918-A | Process for the preparation of silanes, with a tertiary hydrocarbon group in the a-position relative to the silicon atom | WACKER-CHEMIE GMBH (DE) | 2000-12-05 | — | — | US | disclosed |
| EP-0985674-A1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0963992-A2 | Method for preparation of tertiary-hydrocarbylsilyl compounds | DOW CORNING CORPORATION (US) | 1999-12-15 | — | — | EP | disclosed |
| US-5872274-A | Method for preparation of tertiary-hydrocarbylsilyl compounds | DOW CORNING CORPORATION (US) | 1999-02-16 | — | — | US | disclosed |
| EP-0405560-B2 | Preparation of tertiary-hydrocarbylsilyl compounds | DOW CORNING TORAY SILICONE (JP) | 1998-08-12 | — | — | EP | disclosed |
| US-5068386-A | PREPARATION OF TERTIARY-HYDROCARBYLSILYL COMPOUNDS | DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0405560-A2 | Preparation of tertiary-hydrocarbylsilyl compounds | Dow Corning Toray Silicone Company, Limited (JP) | 1991-01-02 | — | — | EP | disclosed |
| JP-H0242088-A | (PHENYLDIMETHYLCARBINYL)SILANE COMPOUND | SHIN ETSU CHEM CO LTD | 1990-02-13 | — | — | JP | disclosed |
| US-4748262-A | (Phenyl dimethyl carbinyl) silane compound and a method for the preparation thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-05-31 | — | — | US | disclosed |
| JP-S6363683-A | (PHENYLDIMETHYLCARBINYL)SILANE COMPOUND AND PRODUCTION THEREOF | SHIN ETSU CHEM CO LTD | 1988-03-22 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142791-A1 | Solid Electrolyte Membrane for Fuel Cell and Process for Producing Same | LNPK, KCNJ1, EPCAM | ALDH1A1 2851/4885ALOX15 1858/4885ESR1 265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.