SCHEMBL705336

SCHEMBL705336

O=C(Oc1cc(O)cc(O)c1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.59
MAPT P10636 4/20 0.59
TDP1 Q9NUW8 2/20 0.59
MEN1 O00255 2/20 0.59
L3MBTL1 Q9Y468 1/20 0.56
PARP10 Q53GL7 1/20 0.55
NSD2 O96028 1/20 0.55
ESR1 P03372 3/20 0.53
ESR2 Q92731 3/20 0.53
ALDH1A1 P00352 1/20 0.51
PKM P14618 1/20 0.51
F2 P00734 1/20 0.50
LMNA P02545 1/20 0.50
RAB9A P51151 1/20 0.49
PRSS1 P07477 1/20 0.49
ACR P10323 1/20 0.49
TMPRSS15 P98073 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
CA12 O43570 2/20 0.47
CA9 Q16790 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17383940 0.96 KMT2A (0.59) KMT2AMAPTTDP1MEN1L3MBTL1
SCHEMBL23212138 0.88 EGFR (0.53) KMT2AMAPTTDP1MEN1L3MBTL1
SCHEMBL17376972 0.88 MAPT (0.53) KMT2AMAPTTDP1MEN1L3MBTL1
SCHEMBL2755026 0.87 KMT2A (0.68) KMT2AMAPTTDP1MEN1L3MBTL1
SCHEMBL9299759 0.86 NSD2 (0.73) KMT2AMAPTTDP1MEN1L3MBTL1
SCHEMBL8205792 0.86 CA12 (0.52) KMT2AMAPTTDP1MEN1ESR1
SCHEMBL321816 0.85 TSHR (0.59) KMT2AMAPTTDP1MEN1L3MBTL1
Benzoic Acid 3-Hydroxyphenyl Ester SCHEMBL78117 0.85 ESR1 (0.71) KMT2AMAPTTDP1MEN1L3MBTL1
Benzoic Acid 3-Hydroxyphenyl Ester SCHEMBL31650796 0.85 ESR1 (0.71) KMT2AMAPTTDP1MEN1L3MBTL1
SCHEMBL10960406 0.84 NSD2 (0.70) KMT2AMAPTTDP1MEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3161063-B1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-06 EP claimed
US-10100181-B2 Stabilized moisture-curable polymeric compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2018-10-16 US claimed
US-20170210892-A1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2017-07-27 US claimed
EP-3161063-A1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS Dow Global Technologies LLC (US) 2017-05-03 EP claimed
WO-2015200016-A1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-12-30 WO claimed
US-20140194499-A1 Polyprenylated Benzoylphloroglucinols With Anticancer Activity HONG KONG BAPTIST UNIVERSITY (HK) 2014-07-10 US claimed
US-12521410-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2026-01-13 US disclosed
US-20240180945-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2024-06-06 US disclosed
EP-3161063-B1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-06 EP disclosed
US-11793823-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-24 US disclosed
US-11793823-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-24 US disclosed
US-11793823-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-24 US disclosed
CN-115836062-A Compound and medical application thereof 心悦生医股份有限公司 2023-03-21 CN disclosed
WO-2006081537-A2 NOVEL AROMATIC PRENYLTRANSFERASES, NUCLEIC ACIDS ENCODING SAME AND USES THEREFOR THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2006-08-03 WO disclosed
EP-0549339-B1 Photosensitive composition MITSUBISHI CHEM CORP (JP) 1997-05-14 EP disclosed
US-5338643-A O-quinonediazide photosensitive composition containing s-triazine compound, novolak resin, vinyl-based polymer and a dye MITSUBISHI KASEI CORPORATION (JP) 1994-08-16 US disclosed
EP-0549339-A1 Photosensitive composition Mitsubishi Chemical Corporation (JP) 1993-06-30 EP disclosed
US-4202833-A INTERMEDIATES TO BISPHENOL CARBONATES THE UPJOHN COMPANY (US) 1980-05-13 US disclosed
US-4200763-A CHEMICAL INTERMEDIATE THE UPJOHN COMPANY (US) 1980-04-29 US disclosed
US-4164510-A METAL PHTHALOCYANINE, TERT-ALKYL PEROXIDE AS CATALYST THE UPJOHN COMPANY (US) 1979-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140194499-A1 Polyprenylated Benzoylphloroglucinols With Anticancer Activity NUDC, PGC, GANC KMT2A 2825/4885MAPT 4628/4885TDP1 2146/4885
US-11793823-B2 Compounds and pharmaceutical uses thereof HRH4, OR10J3, CYP3A5 KMT2A 4419/4885MAPT 2751/4885TDP1 4760/4885
US-20240180945-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF HRH4, OR10J3, CYP3A5 KMT2A 4419/4885MAPT 2751/4885TDP1 4760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.