Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 5/20 | 0.49 |
| ▸ | KDM8 | Q8N371 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467197 | 0.84 | KMT2A (0.42) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7119630 | 0.77 | MEN1 (0.41) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4686653 | 0.76 | TSHR (0.55) | KDM4EMEN1KMT2ARAB9AMAPT | |
| SCHEMBL16519973 | 0.76 | TDP1 (0.48) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL11734394 | 0.74 | KDM4E (0.49) | ASPHKDM8KDM4EMEN1KMT2A | |
| SCHEMBL27971912 | 0.74 | KDM4E (0.49) | ASPHKDM8KDM4EMEN1KMT2A | |
| SCHEMBL29178118 | 0.74 | KDM4E (0.49) | ASPHKDM8KDM4EMEN1KMT2A | |
| SCHEMBL28577900 | 0.73 | KDM4E (0.48) | ASPHKDM8KDM4EMEN1KMT2A | |
| SCHEMBL1245681 | 0.73 | TSHR (0.51) | ASPHKDM8KDM4EMAPTPOLB | |
| SCHEMBL30380021 | 0.73 | KDM4E (0.48) | ASPHKDM8KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003026664-A1 | 2-PHENYLAMINO-4- (5-PYRAZOLYLAMINO) -PYRAMIDINE DERIVATIVES AS KINASE INHIBITORS, IN PARTICULAR, SRC KINASE INHIBITORS | BAYER CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |